Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type	Study_count
Total_Studies	2343
interventional	1822
Observational	490
Registry	31

Studies over Time

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	572
Drug\|placebo	525
Behavioral	199
Other	149
Device	73
Biological\|placebo	49
Biological	39
Procedure	34
Dietary Supplement	22
Dietary Supplement\|placebo	20
Device\|Drug	18
Behavioral\|Other	14
Drug\|Other	12
Device\|Other	10
Diagnostic Test	9
Device\|placebo	7
Drug\|Procedure	7
Other\|placebo	5
Behavioral\|Device	4
Combination Product	4
Dietary Supplement\|Drug	4
Behavioral\|Drug	3
Biological\|Drug	3
Dietary Supplement\|Other	3
Drug\|Other\|placebo	3
Other\|Procedure	3
Behavioral\|placebo	2
Biological\|Drug\|placebo	2
Biological\|Other	2
Biological\|Procedure	2
Diagnostic Test\|Other	2
Drug\|placebo\|Radiation	2
placebo	2
Behavioral\|Device\|Other	1
Behavioral\|Drug\|Other	1
Biological\|Device\|Other\|Procedure	1
Biological\|Dietary Supplement	1
Biological\|Drug\|Radiation	1
Biological\|Other\|placebo	1
Combination Product\|placebo	1
Device\|Drug\|Other	1
Device\|Other\|placebo	1
Device\|Other\|Procedure	1
Device\|Procedure	1
Dietary Supplement\|Other\|placebo	1
Drug\|placebo\|Procedure	1
Drug\|Radiation	1
Genetic	1
Genetic\|Other	1
Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	601
NA	221
United Kingdom	124
Canada	84
Germany	48
Brazil	33
Denmark	32
France	31
Japan	29
China	27
Netherlands	20
Spain	18
Sweden	18
Belgium	17
Italy	17
Poland	15
United States\|Canada	14
Australia	13
Korea, Republic of	13
Turkey	12
New Zealand	8
Thailand	8
Finland	7
Germany\|United Kingdom	7
India	5
Switzerland	5
Taiwan	5
United States\|Puerto Rico	5
Egypt	4
Hong Kong	4
Israel	4
United States\|United Kingdom	4
Belgium\|Germany	3
China\|Korea, Republic of\|Philippines	3
Ireland	3
Netherlands\|United Kingdom	3
Norway	3
Pakistan	3
Poland\|Ukraine	3
United States\|Australia	3
Argentina	2
Australia\|New Zealand	2
Austria	2
Bangladesh	2
Canada\|Sweden	2
France\|Germany	2
Germany\|Netherlands\|United Kingdom	2
Greece	2
Lithuania	2
Puerto Rico	2
Qatar	2
Russian Federation	2
Sweden\|United Kingdom	2
Tunisia	2
United States\|Argentina\|Australia\|Canada\|Chile\|France\|Germany\|Korea, Republic of\|Poland\|Romania\|Russian Federation\|Ukraine\|United Kingdom	2
United States\|Argentina\|Brazil\|Canada\|Philippines	2
United States\|Costa Rica\|Guatemala\|Hungary\|Mexico\|Poland\|Russian Federation	2
Argentina\|Australia\|Brazil\|Canada\|China\|France\|Germany\|India\|Indonesia\|Malaysia\|Mexico\|Philippines\|Singapore\|South Africa\|Spain\|Thailand\|Vietnam	1
Argentina\|Australia\|Colombia\|France\|Korea, Republic of\|Spain\|United Kingdom	1
Argentina\|Austria\|Croatia\|Estonia\|Guatemala\|Hungary\|India\|Italy\|Korea, Republic of\|Latvia\|Poland\|Slovakia	1
Argentina\|Belarus\|Bulgaria\|Czechia\|Germany\|Hungary\|Italy\|Lithuania\|Poland\|Portugal\|Romania\|Russian Federation\|Slovakia\|Spain\|Turkey\|Ukraine\|United Kingdom	1
Argentina\|Belgium\|Brazil\|United States\|Canada\|Colombia\|Denmark\|France\|Germany\|Italy\|Mexico\|Poland\|Russian Federation\|Spain\|Sweden\|Taiwan\|United Kingdom	1
Argentina\|Brazil\|China\|Costa Rica\|Hungary\|India\|Japan\|Korea, Republic of\|Malaysia\|Peru\|Philippines\|Thailand	1
Argentina\|Brazil\|Costa Rica\|Poland	1
Argentina\|Brazil\|Germany\|Israel\|Russian Federation	1
Argentina\|Chile\|Colombia\|Czechia\|Germany\|Greece\|Hungary\|India\|Israel\|Mexico\|Peru\|Poland\|Russian Federation\|Serbia\|Singapore\|Slovakia\|South Africa\|Spain\|Taiwan\|Turkey\|Vietnam	1
Argentina\|Colombia\|Costa Rica\|Mexico\|Peru\|Turkey\|Venezuela	1
Argentina\|Malaysia\|Peru\|Philippines\|Ukraine	1
Australia\|Austria\|Belgium\|Bulgaria\|Canada\|Estonia\|Finland\|Germany\|Ireland\|Latvia\|Macedonia, The Former Yugoslav Republic of\|Netherlands\|New Zealand\|Spain\|United Kingdom	1
Australia\|Belgium\|France\|South Africa\|Spain	1
Australia\|Brazil\|Bulgaria\|Canada\|Chile\|China\|Hungary\|Korea, Republic of\|Mexico\|Peru\|Philippines\|Poland\|Romania\|Russian Federation\|South Africa\|Ukraine\|United Kingdom\|Vietnam	1
Australia\|Canada\|Czech Republic\|Hungary\|Poland\|South Africa\|Spain	1
Australia\|New Zealand\|Slovakia\|Sweden\|United Kingdom	1
Australia\|New Zealand\|Sweden	1
Austria\|Belgium\|Denmark\|Finland\|France\|Germany\|Greece\|Italy\|Russian Federation\|Slovakia\|South Africa\|Spain\|Turkey\|United Kingdom	1
Austria\|Canada\|Germany\|Poland\|South Africa	1
Austria\|Czech Republic\|Estonia\|Germany\|Latvia	1
Austria\|Germany	1
Austria\|Germany\|Hungary\|Slovenia	1
Austria\|Germany\|Poland\|Romania\|Slovakia\|Slovenia	1
Austria\|Germany\|Ukraine	1
Austria\|Italy\|Poland\|Spain	1
Austria\|Poland\|Ukraine	1
Belarus\|Russian Federation	1
Belgium\|Argentina\|Australia\|Austria\|Bulgaria\|Canada\|Chile\|China\|Colombia\|Croatia\|Denmark\|Estonia\|Finland\|France\|Germany\|Greece\|Hungary\|India\|Latvia\|Ireland\|Israel\|Italy\|Japan\|Jordan\|Lebanon\|Lithuania\|Mexico\|Netherlands\|Peru\|Philippines\|Poland\|Portugal\|Romania\|Russian Federation\|Slovakia\|Slovenia\|South Africa\|Spain\|Sweden\|Switzerland\|Thailand\|United Kingdom\|Vietnam	1
Belgium\|Canada\|Denmark\|Germany\|Greece\|Hungary\|Ireland\|Israel\|Italy\|Norway\|Poland\|Portugal\|Spain\|Sweden\|Switzerland\|Turkey\|United Kingdom	1
Belgium\|Canada\|Denmark\|Germany\|Netherlands\|United Kingdom	1
Belgium\|Canada\|Estonia\|Germany\|Hungary\|India\|Japan\|Latvia\|Lithuania\|Malaysia\|Netherlands\|Poland\|Russian Federation\|Slovakia\|Thailand\|Turkey\|Ukraine	1
Belgium\|Colombia\|Croatia\|Germany\|Guatemala\|Hungary\|Philippines\|Russian Federation\|Slovakia\|South Africa\|Turkey	1
Belgium\|Czech Republic\|Germany\|Hungary\|Israel\|Poland\|Russian Federation\|South Africa\|Spain\|United Kingdom	1
Belgium\|Denmark\|France\|Italy\|Latvia\|Lithuania\|Netherlands\|Norway\|Poland\|Russian Federation\|Spain\|Sweden	1
Belgium\|Estonia\|Finland\|France\|Germany\|Italy\|Latvia\|Netherlands\|Spain\|Sweden	1
Belgium\|Finland\|France\|Germany\|Greece\|Iceland\|Ireland\|Italy\|Netherlands\|Norway\|Russian Federation\|Spain\|Sweden\|United Kingdom	1
Belgium\|France\|Italy\|Netherlands\|Spain\|Switzerland\|United Kingdom	1
Belgium\|Germany\|United Kingdom	1
Belgium\|Luxembourg	1
Belgium\|United Kingdom	1
Brazil\|Bulgaria\|Chile\|Croatia\|Estonia\|Germany\|Greece\|Hungary\|Italy\|Mexico\|Romania\|Russian Federation\|South Africa	1
Brazil\|Germany\|Hungary\|India\|Netherlands\|Poland\|South Africa\|Spain\|Switzerland	1
Brazil\|Germany\|Hungary\|Poland\|Portugal\|South Africa	1
Bulgaria	1
Bulgaria\|Australia\|Brazil\|Chile\|Colombia\|Czechia\|France\|Germany\|Hungary\|Korea, Republic of\|Mexico\|New Zealand\|Peru\|Philippines\|Poland\|Romania\|Russian Federation\|Saudi Arabia\|Slovakia\|South Africa\|Spain\|Sweden\|Thailand\|Ukraine\|Vietnam	1
Bulgaria\|Canada\|Czech Republic\|Germany\|Hungary\|Mexico\|Poland\|Romania\|Russian Federation\|Slovakia\|South Africa\|Ukraine\|United Kingdom	1
Bulgaria\|Canada\|Germany\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Slovakia	1
Bulgaria\|Chile\|Colombia\|Estonia\|Germany\|Hungary\|India\|Italy\|Japan\|Korea, Republic of\|Latvia\|Lithuania\|Malaysia\|Peru\|Philippines\|Poland\|Russian Federation\|Slovakia\|South Africa\|Sweden\|Thailand\|Vietnam	1
Bulgaria\|China\|Germany\|Netherlands\|Romania\|United Kingdom	1
Bulgaria\|Czech Republic\|Germany\|Hungary\|Poland\|Russian Federation\|Ukraine	1
Bulgaria\|Czech Republic\|Hungary\|Poland	1
Bulgaria\|Czechia\|France\|Hungary\|India\|Spain	1
Bulgaria\|Czechia\|Hungary\|India\|Poland\|Romania\|Russian Federation\|Ukraine	1
Bulgaria\|Denmark\|Poland\|United Kingdom	1
Bulgaria\|France\|Germany\|Hungary\|Italy\|Poland\|Romania\|Russian Federation\|Slovakia\|Spain\|Ukraine	1
Bulgaria\|Germany	1
Bulgaria\|Germany\|Hungary\|Italy\|Poland\|United Kingdom	1
Bulgaria\|Germany\|Hungary\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|Ukraine	1
Bulgaria\|Germany\|Italy\|Netherlands\|Poland	1
Bulgaria\|Germany\|Poland\|Romania\|United Kingdom	1
Bulgaria\|Germany\|South Africa	1
Bulgaria\|Hungary\|India\|Poland\|Romania	1
Bulgaria\|Hungary\|Poland\|Romania\|Russian Federation\|Ukraine	1
Bulgaria\|Italy\|Ukraine	1
Bulgaria\|Poland\|Ukraine	1
Canada\|Belgium\|Denmark\|France\|Germany\|Italy\|Netherlands\|South Africa	1
Canada\|Denmark\|United Kingdom	1
Canada\|France\|Germany\|Hungary\|India\|Italy	1
Canada\|France\|United States\|Argentina\|Belgium\|Germany\|Netherlands\|Spain\|Sweden	1
Canada\|Germany	1
Canada\|Hungary\|South Africa	1
Canada\|Netherlands\|Sweden	1
Chile\|Croatia\|Czech Republic\|Greece\|Iceland\|Latvia\|Lithuania\|Portugal\|Slovakia\|Slovenia	1
Chile\|United States\|Argentina\|Canada\|Czech Republic\|France\|Germany\|Japan\|Korea, Republic of\|Mexico\|Philippines\|Poland\|Russian Federation\|Spain\|United Kingdom	1
China\|India\|	1
China\|India\|Indonesia\|Taiwan\|Thailand	1
China\|Korea, Republic of\|Philippines\|Taiwan	1
Colombia	1
Croatia\|Czechia\|Germany\|Italy\|Latvia\|Poland\|Romania\|Slovakia	1
Cyprus\|Greece\|Israel	1
Czech Republic	1
Czech Republic\|Germany\|Poland\|Russian Federation\|Ukraine	1
Czech Republic\|India\|Poland\|Russian Federation\|United Kingdom	1
Czechia\|France\|Germany\|Hungary\|Poland\|Romania	1
Czechia\|United States\|Argentina\|Australia\|Belgium\|Canada\|Chile\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Russian Federation\|Spain\|Ukraine\|United Kingdom	1
Denmark\|Finland\|Norway	1
Denmark\|Germany\|Netherlands	1
Denmark\|Hungary\|Poland\|Sweden	1
Denmark\|Switzerland	1
Denmark\|United Kingdom	1
El Salvador	1
Estonia\|Finland	1
Finland\|Austria\|Belgium\|Czech Republic\|Denmark\|France\|Germany\|Hungary\|Israel\|Italy\|Netherlands\|Poland\|Russian Federation\|Spain\|Sweden\|United Kingdom	1
Finland\|Norway\|Sweden	1
Finland\|United Kingdom	1
France\|Denmark\|Germany\|Spain\|Sweden\|United Kingdom	1
France\|Germany\|Hungary\|South Africa	1
France\|Germany\|Italy	1
France\|Germany\|Netherlands\|Spain	1
France\|Germany\|Netherlands\|United Kingdom	1
France\|Germany\|Poland	1
France\|United States\|Argentina\|Canada\|Czechia\|Finland\|Germany\|Guatemala\|Hungary\|India\|Israel\|Italy\|Korea, Republic of\|Mexico\|Panama\|Poland\|Portugal\|Romania\|Russian Federation\|Singapore\|Slovakia\|South Africa\|Turkey\|United Kingdom	1
Georgia	1
Georgia\|United States\|Hungary\|Russian Federation\|Ukraine	1
Germany\|Hungary\|Latvia\|Lithuania\|Russian Federation\|Ukraine	1
Germany\|Hungary\|Netherlands\|Poland\|Romania\|United Kingdom	1
Germany\|Hungary\|Poland\|Romania\|United Kingdom	1
Germany\|Hungary\|South Africa	1
Germany\|India	1
Germany\|Italy	1
Germany\|Lithuania\|Poland	1
Germany\|Netherlands\|South Africa	1
Germany\|New Zealand\|United Kingdom	1
Germany\|Poland\|Ukraine	1
Germany\|South Africa	1
Germany\|Sweden\|United Kingdom	1
Germany\|United States\|Australia\|Bulgaria\|Canada\|Chile\|Croatia\|Israel\|Mexico\|New Zealand\|Peru\|Philippines\|Russian Federation\|South Africa\|Thailand\|Ukraine	1
Germany\|United States\|Hungary\|Poland	1
Hungary	1
Hungary\|Poland\|Russian Federation	1
Hungary\|Poland\|United Kingdom	1
Hungary\|United States\|Argentina\|Australia\|Belgium\|Canada\|Czechia\|France\|Germany\|Israel\|Japan\|Korea, Republic of\|Mexico\|New Zealand\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|Turkey\|Ukraine	1
Indonesia	1
Iran, Islamic Republic of	1
Ireland\|United Kingdom	1
Italy\|Russian Federation\|Spain\|Ukraine	1
Japan\|Korea, Republic of	1
Japan\|United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|Chile\|Colombia\|Denmark\|France\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
Japan\|United States\|Argentina\|Australia\|Canada\|Germany\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|United Kingdom	1
Japan\|United States\|Argentina\|Brazil\|Mexico\|Romania\|Russian Federation\|Slovakia\|South Africa\|Ukraine	1
Japan\|United States\|Bulgaria\|Germany\|Hungary\|Poland\|South Africa\|Ukraine	1
Malaysia	1
Malaysia\|Taiwan	1
Mexico	1
New Zealand\|South Africa	1
New Zealand\|United Kingdom	1
Norway\|Sweden	1
Panama	1
Peru	1
Peru\|United States\|Argentina\|Belgium\|Bulgaria\|Canada\|Germany\|Hungary\|Mexico\|New Zealand\|Poland\|Romania\|Russian Federation\|Ukraine	1
Peru\|United States\|Argentina\|Brazil\|Bulgaria\|Canada\|Colombia\|Mexico\|Poland\|Russian Federation	1
Philippines	1
Poland\|United States\|Australia\|France\|Ukraine\|United Kingdom	1
Poland\|United States\|Belgium\|France\|Germany\|Netherlands\|Ukraine	1
Poland\|United States\|Canada\|Czech Republic\|Hungary\|Russian Federation\|South Africa\|Ukraine	1
Russian Federation\|Ukraine	1
Russian Federation\|United Kingdom	1
Saudi Arabia	1
Singapore	1
Slovakia\|United States\|Argentina\|Canada\|Czechia\|Germany\|Serbia\|South Africa\|Spain\|Ukraine\|United Kingdom	1
Slovenia	1
South Africa\|United States\|Argentina\|Chile\|Hungary\|Mexico\|Peru\|Poland\|Romania\|Ukraine	1
Sweden\|Denmark\|Finland\|Germany\|Norway\|United Kingdom	1
Uganda	1
Ukraine\|United States\|Argentina\|Australia\|Canada\|France\|Germany\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Romania\|Russian Federation\|Spain	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|China\|Denmark\|Estonia\|Finland\|France\|Germany\|Greece\|Guatemala\|Hungary\|Iceland\|Ireland\|Latvia\|Lithuania\|Philippines\|Poland\|Romania\|Singapore\|Spain\|Switzerland\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Austria\|Brazil\|Canada\|France\|Germany\|Israel\|Japan\|Korea, Republic of\|Russian Federation\|Saudi Arabia\|South Africa\|Taiwan\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Austria\|Brazil\|Canada\|France\|Germany\|Israel\|Korea, Republic of\|Poland\|Russian Federation\|Saudi Arabia\|South Africa\|Taiwan\|Turkey\|Ukraine\|Vietnam	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|Czech Republic\|Germany\|Guatemala\|Hungary\|Latvia\|Lithuania\|Poland\|Romania\|Russian Federation\|Slovakia\|Ukraine	1
United States\|Argentina\|Australia\|Belgium\|Bulgaria\|Canada\|Czechia\|France\|Germany\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|New Zealand\|Peru\|Poland\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Canada\|Chile\|Czechia\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Russian Federation\|Spain\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Canada\|Chile\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Mexico\|Russian Federation\|Spain\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Czechia\|France\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Russian Federation\|Spain\|Ukraine	1
United States\|Argentina\|Australia\|Brazil\|Bulgaria\|Canada\|Chile\|Czechia\|France\|Germany\|Japan\|Korea, Republic of\|Peru\|Philippines\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|Sweden\|Turkey\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Brazil\|Canada\|Chile\|Colombia\|France\|Germany\|Hungary\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Russian Federation\|South Africa\|Spain\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Brazil\|Canada\|Chile\|Colombia\|Hungary\|Italy\|Lithuania\|Mexico\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|Turkey\|Ukraine	1
United States\|Argentina\|Australia\|Brazil\|Canada\|Chile\|Colombia\|Hungary\|Italy\|Lithuania\|Mexico\|Poland\|Russian Federation\|South Africa\|Spain\|Turkey\|Ukraine	1
United States\|Argentina\|Australia\|Bulgaria\|Canada\|Chile\|Czechia\|France\|Germany\|Poland\|Russian Federation\|Spain\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Bulgaria\|Germany\|Guatemala\|Hungary\|Israel\|Latvia\|Mexico\|Philippines\|Portugal\|South Africa\|Ukraine	1
United States\|Argentina\|Australia\|Chile\|France\|Italy\|Japan\|Korea, Republic of\|Mexico\|New Zealand\|Poland\|Russian Federation\|South Africa\|Spain\|Turkey\|Ukraine	1
United States\|Argentina\|Australia\|Germany\|Japan\|Mexico\|Philippines\|Poland\|Romania\|Russian Federation\|Ukraine	1
United States\|Argentina\|Austria\|Bulgaria\|Canada\|Colombia\|France\|Greece\|Guatemala\|Hungary\|India\|Italy\|Japan\|Mexico\|Netherlands\|Peru\|Poland\|Romania\|Russian Federation\|South Africa\|Turkey\|United Kingdom	1
United States\|Argentina\|Belgium\|Brazil\|Canada\|Chile\|Colombia\|Hungary\|Israel\|Italy\|Mexico\|Netherlands\|Poland\|Romania\|Russian Federation\|Spain\|Ukraine	1
United States\|Argentina\|Belgium\|Brazil\|Canada\|Colombia\|France\|Hungary\|Israel\|Mexico\|Netherlands\|Poland\|Sweden	1
United States\|Argentina\|Belgium\|Bulgaria\|Canada\|Czechia\|Estonia\|France\|Germany\|Greece\|Italy\|Netherlands\|Norway\|Peru\|Russian Federation\|Slovakia\|Spain\|Ukraine\|United Kingdom	1
United States\|Argentina\|Belgium\|Bulgaria\|Canada\|Czechia\|Germany\|Korea, Republic of\|New Zealand\|Peru\|Poland\|Romania\|Russian Federation\|South Africa\|Ukraine	1
United States\|Argentina\|Belgium\|Bulgaria\|Colombia\|Germany\|Hungary\|Korea, Republic of\|Peru\|Poland\|Slovakia\|Spain\|Taiwan\|Ukraine\|Vietnam	1
United States\|Argentina\|Belgium\|Canada\|Chile\|France\|Germany\|Korea, Republic of\|Netherlands\|Peru\|Philippines\|Poland\|Russian Federation\|South Africa\|Sweden\|Thailand	1
United States\|Argentina\|Belgium\|Canada\|Czechia\|Germany\|Italy\|Netherlands\|Poland	1
United States\|Argentina\|Belgium\|Canada\|France\|Germany\|Israel\|Japan\|Netherlands\|South Africa	1
United States\|Argentina\|Belgium\|Czech Republic\|Germany\|Poland\|Russian Federation	1
United States\|Argentina\|Belgium\|Denmark\|France\|Germany\|Israel\|Slovakia	1
United States\|Argentina\|Brazil\|Bulgaria\|Chile\|Colombia\|Czech Republic\|France\|Germany\|India\|Italy\|Korea, Republic of\|Mexico\|Panama\|Peru\|Philippines\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Slovakia\|South Africa\|Thailand\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Argentina\|Brazil\|Canada\|Colombia\|Costa Rica\|Panama\|Peru\|Philippines\|Taiwan	1
United States\|Argentina\|Brazil\|Canada\|Colombia\|Czechia\|France\|Germany\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Peru\|Poland\|Portugal\|Slovakia\|South Africa\|Spain\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Argentina\|Brazil\|Canada\|France\|Germany\|Greece\|Korea, Republic of\|Mexico\|Peru\|Romania\|Russian Federation\|Slovakia\|Taiwan\|Ukraine	1
United States\|Argentina\|Bulgaria\|Canada\|Chile\|Colombia\|Croatia\|Hong Kong\|Hungary\|India\|Mexico\|Philippines\|Puerto Rico\|Singapore\|Taiwan\|Thailand	1
United States\|Argentina\|Bulgaria\|Canada\|Chile\|France\|Germany\|Korea, Republic of\|Poland\|Spain\|Turkey\|Ukraine	1
United States\|Argentina\|Bulgaria\|Canada\|Czech Republic\|France\|Germany\|Hungary\|Italy\|Mexico\|Poland\|Portugal\|Slovakia\|Switzerland	1
United States\|Argentina\|Canada\|Chile\|Germany\|Japan\|Philippines\|Poland\|Romania\|Sweden\|Ukraine	1
United States\|Argentina\|Canada\|China\|Germany\|Italy\|Japan\|Mexico\|Poland\|Romania\|Russian Federation\|South Africa\|Spain	1
United States\|Argentina\|Canada\|Czech Republic\|France\|Germany\|Hungary\|Italy\|Peru\|Slovakia\|Spain\|Turkey	1
United States\|Argentina\|Chile\|France\|Mexico\|Russian Federation	1
United States\|Argentina\|Chile\|Germany\|Mexico\|Netherlands\|Poland\|Romania\|Russian Federation\|Sweden\|Ukraine	1
United States\|Argentina\|Chile\|Korea, Republic of\|Netherlands\|Philippines	1
United States\|Argentina\|Chile\|Mexico\|Poland\|Russian Federation\|Turkey\|Ukraine	1
United States\|Argentina\|Chile\|Peru\|Puerto Rico	1
United States\|Argentina\|Chile\|Russian Federation\|Thailand	1
United States\|Argentina\|Colombia\|Mexico\|Peru	1
United States\|Argentina\|Czechia\|Germany\|Serbia\|Slovakia\|Ukraine	1
United States\|Argentina\|Germany	1
United States\|Argentina\|Germany\|Hungary\|Mexico\|Philippines\|Saudi Arabia\|Slovakia\|South Africa\|Turkey	1
United States\|Argentina\|Germany\|Korea, Republic of\|Poland\|Turkey\|Ukraine	1
United States\|Argentina\|Germany\|Peru\|Poland	1
United States\|Argentina\|Germany\|Poland\|Russian Federation	1
United States\|Argentina\|Germany\|Russian Federation\|Ukraine	1
United States\|Argentina\|Netherlands\|Brazil\|Chile\|Czechia\|Germany\|Korea, Republic of\|Mexico\|Romania\|Russian Federation\|Spain	1
United States\|Argentina\|Poland\|Romania\|Russian Federation\|South Africa	1
United States\|Argentina\|Slovakia\|Canada\|Czechia\|Greece\|India\|Israel\|Italy\|Japan\|Lebanon\|Malaysia\|Mexico\|Netherlands\|Russian Federation\|Serbia\|South Africa\|Spain\|Taiwan	1
United States\|Australia\|Belgium\|Canada\|Czechia\|Denmark\|France\|Mexico\|Netherlands\|New Zealand\|Poland\|Puerto Rico\|Slovakia\|Slovenia\|Spain\|United Kingdom	1
United States\|Australia\|Belgium\|Chile\|Colombia\|Czech Republic\|Denmark\|Hungary\|Israel\|Malaysia\|New Zealand\|Philippines\|Poland\|Russian Federation\|South Africa\|Sweden\|Thailand	1
United States\|Australia\|Brazil\|Bulgaria\|Czech Republic\|France\|Italy\|Korea, Republic of\|Mexico\|Peru\|Poland\|Russian Federation\|South Africa\|Spain\|Turkey\|United Kingdom\|Vietnam	1
United States\|Australia\|Brazil\|Canada\|Denmark\|Netherlands\|United Kingdom	1
United States\|Australia\|Bulgaria\|Canada\|Chile\|Czechia\|Estonia\|France\|Germany\|Mexico\|Netherlands\|Peru\|Poland\|Russian Federation\|South Africa\|Thailand	1
United States\|Australia\|Bulgaria\|Canada\|Croatia\|Germany\|Greece\|Hungary\|Ireland\|Israel\|New Zealand\|Poland\|Romania\|Russian Federation\|Serbia\|South Africa\|Spain\|Ukraine\|United Kingdom	1
United States\|Australia\|Bulgaria\|Germany\|Hungary\|Israel\|Poland\|Russian Federation\|Serbia\|Singapore\|South Africa\|Sweden\|Ukraine	1
United States\|Australia\|Canada\|Chile\|Costa Rica\|Germany\|Latvia\|Lithuania\|Mexico\|Peru\|Poland\|Russian Federation\|Spain	1
United States\|Australia\|Canada\|Colombia\|Korea, Republic of\|Mexico\|New Zealand\|Peru\|Philippines\|Taiwan	1
United States\|Australia\|Canada\|Czech Republic\|France\|Germany\|Mexico\|Netherlands\|Poland\|United Kingdom	1
United States\|Australia\|Canada\|Denmark\|Germany\|Italy\|Japan\|Netherlands\|New Zealand\|Russian Federation\|Serbia\|South Africa\|Turkey\|Ukraine\|United Kingdom	1
United States\|Australia\|Canada\|Denmark\|Germany\|Italy\|Japan\|Netherlands\|Russian Federation\|Serbia\|South Africa\|Turkey\|Ukraine\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|United Kingdom	1
United States\|Australia\|Canada\|Germany\|Russian Federation\|Sweden\|United Kingdom	1
United States\|Australia\|Canada\|Mexico\|Russian Federation\|Ukraine	1
United States\|Australia\|New Zealand\|South Africa	1
United States\|Austria\|Argentina\|Australia\|Belgium\|Bulgaria\|Canada\|Chile\|Colombia\|Croatia\|Czechia\|Germany\|Hungary\|Italy\|Korea, Republic of\|Latvia\|Lithuania\|Malaysia\|Mexico\|Peru\|Philippines\|Poland\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Taiwan\|Thailand\|Ukraine\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|Czechia\|France\|Germany\|Poland\|Spain\|Ukraine\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|Denmark\|Finland\|France\|Germany\|Italy\|Netherlands\|Norway\|Spain\|Sweden\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|Finland\|Hungary\|Korea, Republic of\|Netherlands\|Poland\|Russian Federation	1
United States\|Austria\|Croatia\|Czech Republic\|Finland\|France\|Greece\|Hungary\|India\|Ireland\|Italy\|New Zealand\|Norway\|Pakistan\|Philippines\|Poland\|Portugal\|Russian Federation\|Singapore\|South Africa\|Spain\|Taiwan\|Thailand\|United Kingdom	1
United States\|Austria\|Germany\|Hungary\|Slovakia\|Slovenia	1
United States\|Austria\|Germany\|Italy\|Korea, Republic of\|New Zealand\|Sweden\|Turkey\|United Kingdom	1
United States\|Belgium\|Bulgaria\|Canada\|Denmark\|France\|Germany\|Hungary\|Italy\|Latvia\|Netherlands\|Portugal\|Russian Federation\|Spain\|United Kingdom	1
United States\|Belgium\|Bulgaria\|Czech Republic\|France\|Germany\|Hungary\|Netherlands\|Poland\|Sweden\|United Kingdom	1
United States\|Belgium\|Canada\|France\|Germany\|Korea, Republic of\|Netherlands\|Poland\|Taiwan\|United Kingdom	1
United States\|Belgium\|Colombia\|Czech Republic\|Germany\|India\|Korea, Republic of\|Poland\|Romania\|South Africa	1
United States\|Belgium\|Finland\|Germany\|Korea, Republic of\|Latvia\|Lithuania\|Malaysia\|Netherlands\|Philippines\|Ukraine	1
United States\|Belgium\|Germany\|Japan\|Latvia\|Lithuania	1
United States\|Belgium\|Germany\|Korea, Republic of\|Romania	1
United States\|Belgium\|Germany\|Poland\|Romania	1
United States\|Brazil\|Bulgaria\|Canada\|Colombia\|Germany\|Hungary\|India\|Israel\|Italy\|Korea, Republic of\|Peru\|Puerto Rico\|Russian Federation\|Spain\|Sweden\|Tunisia\|Vietnam	1
United States\|Brazil\|Bulgaria\|Canada\|Czech Republic\|Georgia\|New Zealand\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Slovakia\|South Africa\|United Kingdom	1
United States\|Brazil\|Bulgaria\|Puerto Rico	1
United States\|Brazil\|Canada\|Costa Rica\|Germany	1
United States\|Brazil\|Chile\|Costa Rica\|Estonia\|Israel\|Latvia\|Mexico\|Poland\|Puerto Rico\|Russian Federation	1
United States\|Brazil\|China\|Colombia\|Germany\|India\|Japan\|Mexico\|Peru\|Poland\|Romania	1
United States\|Brazil\|China\|Guatemala\|India\|Japan\|Latvia\|Mexico\|Peru\|Poland\|Russian Federation	1
United States\|Brazil\|Colombia\|Czech Republic\|Hungary\|India\|Korea, Republic of\|Peru\|Slovakia	1
United States\|Brazil\|Latvia\|Puerto Rico	1
United States\|Bulgaria\|Canada\|Estonia\|France\|Germany\|Korea, Republic of\|Mexico\|Peru\|Philippines\|Poland\|Russian Federation\|Slovakia\|Sweden	1
United States\|Bulgaria\|Canada\|Germany\|Guatemala\|Hungary\|Korea, Republic of\|Latvia\|Lithuania\|Norway\|Portugal\|Romania\|Russian Federation\|Sweden\|Ukraine\|United Kingdom	1
United States\|Bulgaria\|China\|Croatia\|Czechia\|Egypt\|Estonia\|Germany\|Guatemala\|Hungary\|India\|Ireland\|Japan\|Korea, Republic of\|Latvia\|Lithuania\|Mexico\|Poland\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|United Kingdom	1
United States\|Bulgaria\|Croatia\|Hungary\|Israel\|Poland\|Serbia\|Spain\|Ukraine	1
United States\|Bulgaria\|Czechia\|Hungary\|Israel\|Japan\|Latvia\|Lithuania\|Serbia\|Slovakia\|South Africa\|Ukraine	1
United States\|Bulgaria\|Georgia\|Germany\|Japan\|Latvia\|Mexico\|Peru\|Philippines\|Poland\|Puerto Rico\|Russian Federation\|South Africa\|Sweden\|Ukraine	1
United States\|Bulgaria\|Germany\|Hungary\|Poland\|Romania\|Ukraine\|United Kingdom	1
United States\|Bulgaria\|Germany\|Mexico\|Peru\|Poland	1
United States\|Bulgaria\|Hungary\|Latvia\|Poland\|Slovakia\|South Africa	1
United States\|Bulgaria\|Japan\|Poland\|Romania\|Ukraine	1
United States\|Canada\|Denmark\|France\|Germany\|Netherlands\|Romania\|United Kingdom	1
United States\|Canada\|Denmark\|Germany\|Sweden\|United Kingdom	1
United States\|Canada\|Denmark\|Germany\|United Kingdom	1
United States\|Canada\|Denmark\|Sweden\|United Kingdom	1
United States\|Canada\|Estonia\|Germany\|Greece\|Korea, Republic of\|Mexico\|Philippines\|Poland\|Romania\|Russian Federation\|Slovakia\|South Africa	1
United States\|Canada\|Estonia\|Poland	1
United States\|Canada\|France\|Germany	1
United States\|Canada\|France\|Germany\|Israel\|United Kingdom	1
United States\|Canada\|France\|Germany\|Netherlands\|Sweden\|United Kingdom	1
United States\|Canada\|France\|Ireland\|Sweden\|United Kingdom	1
United States\|Canada\|Germany\|Hungary\|Poland\|Slovakia	1
United States\|Canada\|Germany\|Italy\|Netherlands\|Spain\|United Kingdom	1
United States\|Canada\|India\|Romania	1
United States\|Canada\|Japan\|Poland	1
United States\|Canada\|Netherlands\|Russian Federation\|Sweden	1
United States\|Canada\|Poland\|Romania\|Russian Federation	1
United States\|Chile\|Germany\|Hungary\|Italy\|Korea, Republic of\|Latvia\|Mexico\|Russian Federation\|Slovakia\|Spain\|Ukraine	1
United States\|Chile\|Germany\|Hungary\|Korea, Republic of\|Philippines	1
United States\|Colombia\|Peru	1
United States\|Costa Rica\|India	1
United States\|Croatia\|Czechia\|Germany\|Hungary\|Poland	1
United States\|Croatia\|Mexico\|Poland\|Ukraine	1
United States\|Estonia\|France\|Germany	1
United States\|France\|Germany\|Jordan\|Netherlands\|United Kingdom	1
United States\|France\|Germany\|Netherlands\|Norway\|Poland\|South Africa\|United Kingdom	1
United States\|Germany	1
United States\|Germany\|Argentina\|Australia\|Belgium\|Canada\|Chile\|Colombia\|Czechia\|France\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|New Zealand\|Poland\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Turkey\|Ukraine\|United Kingdom	1
United States\|Germany\|Japan\|Poland\|Romania\|Russian Federation	1
United States\|Germany\|Japan\|Poland\|Romania\|Ukraine	1
United States\|Germany\|Latvia\|Lithuania\|Slovenia	1
United States\|Germany\|Peru\|Poland\|Ukraine	1
United States\|Germany\|Thailand\|Ukraine	1
United States\|Germany\|United Kingdom	1
United States\|Hungary\|Canada\|Czechia\|Poland\|Russian Federation\|South Africa\|Thailand\|Ukraine	1
United States\|Hungary\|Mexico\|Poland\|Russian Federation\|South Africa	1
United States\|Hungary\|Poland\|United Kingdom	1
United States\|Italy\|Argentina\|Australia\|Austria\|Belgium\|Bulgaria\|Canada\|Chile\|Colombia\|Croatia\|Czechia\|Denmark\|Germany\|Hungary\|Indonesia\|Korea, Republic of\|Latvia\|Lithuania\|Malaysia\|Mexico\|Peru\|Philippines\|Poland\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Japan	1
United States\|Japan\|Canada\|Chile\|Czechia\|Italy\|Mexico\|Philippines\|Russian Federation\|South Africa\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Japan\|Poland\|United Kingdom	1
United States\|Kenya\|Peru\|Puerto Rico	1
United States\|Mexico\|Netherlands\|Peru\|Poland\|Russian Federation	1
United States\|Mexico\|Panama\|Slovakia	1
United States\|Mexico\|Peru\|Romania\|Ukraine	1
United States\|Mexico\|Peru\|Russian Federation	1
United States\|Philippines\|Argentina\|Chile\|Georgia\|Germany\|Japan\|Mexico\|Peru\|Poland\|Puerto Rico\|Slovakia\|South Africa\|Ukraine	1
United States\|Philippines\|Poland\|Romania\|Ukraine	1
United States\|Russian Federation\|Ukraine	1
United States\|South Africa	1
United States\|South Africa\|United Kingdom	1
United States\|Thailand	1
Venezuela	1

Sites per Study

Site_count	Study_Count
1	1056
2	127
3	50
4	38
5	40
6	23
7	24
8	20
9	13
10	15
11	13
12	10
13	12
14	8
15	12
16	12
17	5
18	10
19	12
20	6
21	6
22	4
24	9
25	6
26	4
27	6
28	7
29	5
30	5
31	3
32	5
33	6
34	1
35	6
36	1
37	2
38	2
39	7
40	2
41	5
42	3
43	5
44	3
45	1
46	2
47	4
49	3
50	3
51	2
52	2
53	3
54	3
55	3
56	1
57	7
58	3
59	2
60	4
62	2
63	3
64	3
65	2
66	4
67	1
68	2
69	2
70	3
71	7
73	1
74	4
75	3
76	2
77	1
79	2
80	2
81	1
82	5
84	1
87	4
89	3
90	1
91	1
92	3
93	2
94	1
95	2
96	2
97	1
98	1
99	2
100	2
101	3
102	2
103	1
104	1
106	1
107	2
108	1
109	2
110	1
111	1
113	1
114	2
118	1
121	2
122	2
123	1
125	1
126	1
127	1
128	2
131	1
134	2
135	1
137	2
138	2
139	1
140	1
142	2
143	1
144	1
145	1
146	1
147	1
149	2
150	1
154	2
155	1
165	2
167	1
178	1
179	1
180	1
181	2
183	2
186	1
189	1
200	1
201	1
206	1
210	1
217	1
226	1
230	1
232	1
233	2
234	1
235	1
243	1
244	1
255	1
257	1
281	1
292	1
300	1
342	1
350	1
365	1
389	1
390	1
409	1
431	1
468	1
532	1
808	1
819	1

Phase

Phase	Study_Count
N/A	553
Phase 3	415
Phase 2	393
Phase 4	253
Phase 1	145
Phase 1/Phase 2	26
Phase 2/Phase 3	25
Early Phase 1	12

Number of Arms

Number_of_Arms	Count_of_Studies
1	231
2	871
3	222
4	151
5	43
6	46
7	9
8	7
9	2
10	2
11	2
12	4
13	1
14	1
15	1
16	1
18	1
NA	227

Number of Updates

Count of Versions	Count of Studies
1	142
2	185
3	225
4	193
5	173
6	135
7	127
8	106
9	76
10	49
11	47
12	32
13	26
14	28
15	22
16	13
17	15
18	9
19	7
20	18
21	10
22	10
23	8
24	11
25	13
26	4
27	8
28	4
29	7
30	7
32	5
33	8
34	7
35	1
36	3
37	2
38	1
39	2
40	4
41	4
42	2
43	2
44	6
45	2
46	1
47	1
48	2
49	3
50	2
51	2
53	2
54	1
55	4
57	1
58	4
61	5
62	2
63	2
64	1
65	1
66	2
71	3
73	1
74	1
77	2
79	2
80	1
82	1
83	1
84	1
85	1
90	1
92	1
94	1
99	1
103	1
104	1
106	2
107	1
112	1
139	1
166	1
503	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	16474	1680	9.805952
Contacts/Locations	8067	1407	5.733475
Recruitment Status	2811	1445	1.945329
Study Design	2229	1284	1.735981
None (earliest Version on record)	1822	1822	1.000000
Outcome Measures	1767	949	1.861960
Sponsor/Collaborators	1332	827	1.610641
Arms	1211	784	1.544643
Interventions	1211	784	1.544643
Study Identification	1141	699	1.632332
Eligibility	1132	681	1.662261
Study Description	858	599	1.432387
More Information	823	321	2.563863
Oversight	804	648	1.240741
References	575	437	1.315789
Results	430	430	1.000000
Baseline Characteristics	297	208	1.427885
IPDSharing	281	269	1.044610
Conditions	235	187	1.256684
Participant Flow	154	136	1.132353
Reported Adverse Events	154	135	1.140741
Results Submission Events	147	147	1.000000
Documents	100	89	1.123595
2020 Study Status	2	2	1.000000
Quality Control Review has not concludedReturned: February 13	1	1	1.000000
Quality Control Review has not concludedReturned: June 16	1	1	1.000000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	9.00	1.0000	7.00000	10.00000	2.0000	10	0.0000	5.0000
1st Qu.	24.75	34.0000	22.00000	20.25000	32.0000	45	132.0000	40.0000
Median	48.00	72.5000	36.00000	36.50000	64.0000	144	351.0000	100.0000
Mean	68.00	287.9111	72.52448	52.34615	173.3907	306	561.5795	365.8968
3rd Qu.	61.50	205.5000	60.00000	63.00000	210.0000	408	689.0000	281.2500
Max.	328.00	14978.0000	879.00000	280.00000	2283.0000	2285	12460.0000	11751.0000

Trial Group Type

group_type	Group_Count
Experimental	2097
Active Comparator	931
Placebo Comparator	661
NA	227
No Intervention	166
Other	155
Sham Comparator	27

Intervention Model

intervention_model	Study_Count
Parallel Assignment	1149
Crossover Assignment	347
Single Group Assignment	280
NA	23
Factorial Assignment	17
Sequential Assignment	6

Primary Purpose

primary_purpose	Study_Count
Treatment	1316
Health Services Research	91
Prevention	91
Basic Science	82
Other	64
Supportive Care	61
Diagnostic	57
NA	55
Screening	3
Device Feasibility	2

Observational Studies

Studies by Country

Country	Study_Count
United States	137
NA	89
United Kingdom	40
France	27
Canada	18
Italy	16
Netherlands	13
Spain	13
China	12
Germany	11
Japan	9
Greece	7
Thailand	7
Belgium	6
Israel	6
Hong Kong	5
Korea, Republic of	5
Poland	5
Brazil	4
Russian Federation	3
Switzerland	3
Taiwan	3
Turkey	3
Austria	2
Denmark	2
Finland	2
Hungary	2
Malaysia	2
Portugal	2
Saudi Arabia	2
United Arab Emirates	2
United States\|Puerto Rico	2
Algeria\|Egypt\|Iran, Islamic Republic of\|Iraq\|Jordan\|Kuwait\|Lebanon\|Qatar\|Saudi Arabia\|Tunisia\|United Arab Emirates	1
Argentina	1
Argentina\|Chile\|Colombia\|Costa Rica\|Hong Kong\|Mexico\|Saudi Arabia	1
Australia\|United States\|Argentina\|Brazil\|Canada\|China\|Colombia\|Denmark\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|Norway\|Spain\|Sweden\|United Kingdom	1
Belgium\|Bulgaria\|Czechia\|Denmark\|Germany\|Greece\|Hungary\|Netherlands\|Norway\|Portugal\|Sweden\|United Kingdom	1
Bulgaria\|Czechia\|France\|Germany\|Greece\|Hungary\|Italy\|Netherlands\|Poland\|Romania\|Slovenia\|Spain	1
Chile	1
Colombia	1
Costa Rica	1
Croatia	1
Czech Republic	1
Czechia	1
Egypt	1
Guinea-Bissau	1
Latvia	1
Lithuania	1
Malawi\|South Africa	1
Philippines	1
Puerto Rico	1
Qatar\|Kuwait\|Oman\|United Arab Emirates	1
Romania	1
Serbia	1
Singapore	1
Slovenia	1
Spain\|Croatia\|Denmark\|Ireland\|Italy\|Netherlands\|Norway\|Portugal\|Sweden\|United Kingdom	1
Sweden	1
Taiwan\|Vietnam	1
United States\|Brazil\|Canada\|China\|Germany\|Italy\|Netherlands\|Spain	1
United States\|Canada	1
Vietnam	1

Sites per Study

Site_count	Study_Count
1	372
2	27
3	6
4	13
5	5
6	5
7	1
8	6
9	2
10	4
11	3
12	4
13	3
14	1
15	3
17	1
18	2
19	1
21	1
22	1
24	1
26	2
32	2
34	1
36	1
37	1
40	1
44	1
47	3
51	1
53	1
57	1
75	1
80	1
94	1
98	1
100	1
141	1
153	1
175	1
298	1
703	1
728	1
910	1
1054	1

Number of Updates

Count of Versions	Count of Studies
1	57
2	105
3	95
4	54
5	42
6	28
7	15
8	23
9	6
10	13
11	10
12	5
13	5
14	2
15	2
16	3
17	3
18	2
19	2
20	2
21	1
22	1
23	1
24	1
27	1
28	2
31	1
37	1
39	1
42	1
80	1
89	1
104	1
138	1
174	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	2534	433	5.852194
Contacts/Locations	744	308	2.415584
Recruitment Status	499	335	1.489552
None (earliest Version on record)	490	490	1.000000
Study Design	465	308	1.509740
Study Description	367	122	3.008197
Eligibility	246	165	1.490909
Sponsor/Collaborators	209	166	1.259036
Study Identification	203	146	1.390411
Outcome Measures	177	129	1.372093
Groups	121	94	1.287234
Interventions	121	94	1.287234
References	105	71	1.478873
Oversight	103	88	1.170454
Conditions	35	32	1.093750
IPDSharing	27	25	1.080000
Results	27	27	1.000000
More Information	21	8	2.625000
Documents	8	6	1.333333
Results Submission Events	8	8	1.000000
Baseline Characteristics	5	5	1.000000
Participant Flow	1	1	1.000000
Reported Adverse Events	1	1	1.000000

Enrollment Metrics

Measure	Observational
Min	1.000
1st Qu	60.000
Median	150.000
Mean	9831.966
3rd Qu	699.000
Max	815377.000

Observation Model

observational_model	Study_Count
Cohort	219
NA	87
Case-Only	51
Case-Control	42
Case Control	37
Other	28
Ecologic or Community	8
Case-Crossover	7
Family-Based	4
Defined Population, Natural History	3
Natural History	3
Defined Population	1

Time Perspective

time_perspective	Study_Count
Prospective	272
Cross-Sectional	90
Retrospective	63
NA	53
Other	5
Longitudinal, Prospective	3
Cross-Sectional, Prospective	2
Cross-Sectional, Retrospective	2

Registries

Studies by Country

Country	Study_Count
United States	6
France	3
Turkey	3
Germany	2
Korea, Republic of	2
United Kingdom	2
Australia\|Czechia\|Germany\|Italy\|Netherlands\|South Africa\|Spain\|United Kingdom	1
Canada	1
China	1
Denmark	1
Finland	1
Hong Kong	1
Israel	1
Japan	1
Nepal	1
Russian Federation	1
Spain	1
Switzerland	1
United States\|Puerto Rico	1

Sites per Study

Site_count	Study_Count
1	17
2	4
3	2
7	1
9	1
10	1
19	1
30	1
37	1
79	1
137	1

Number of Updates

Count of Versions	Count of Studies
1	5
2	9
3	3
4	4
5	2
6	1
7	2
8	1
10	1
26	1
28	1
30	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	148	26	5.692308
Contacts/Locations	77	18	4.277778
None (earliest Version on record)	31	31	1.000000
Recruitment Status	22	15	1.466667
Outcome Measures	18	13	1.384615
Study Design	18	11	1.636364
Study Description	11	9	1.222222
Eligibility	10	9	1.111111
Oversight	9	9	1.000000
References	8	5	1.600000
Sponsor/Collaborators	7	5	1.400000
Study Identification	6	4	1.500000
Conditions	5	5	1.000000
IPDSharing	3	3	1.000000
Documents	1	1	1.000000
Groups	1	1	1.000000
Interventions	1	1	1.000000
Results	1	1	1.000000
Results Submission Events	1	1	1.000000

Enrollment Metrics

Measure	Registries
Min	25.0000
1st Qu	95.0000
Median	307.0000
Mean	948.0645
3rd Qu	790.0000
Max	7000.0000

Registry Model

observational_model	Study_Count
Cohort	21
Case-Only	4
Case-Control	3
Other	2
Case Control	1

Time Perspective

time_perspective	Study_Count
Prospective	28
Cross-Sectional	2
Other	1

Follow-up

target_duration	Study_Count
5 Years	3
1 Day	2
12 Months	2
2 Months	2
3 Months	2
3 Years	2
1 Month	1
1 Year	1
10 Years	1
12 Weeks	1
12 Years	1
13 Months	1
15 Years	1
156 Weeks	1
2 Years	1
20 Months	1
22 Months	1
35 Years	1
5 Weeks	1
6 Months	1
6 Years	1
7 Years	1
8 Weeks	1
9 Months	1

intervention_type	Study_Count
Drug	572
Drug\|placebo	525
Behavioral	199
Other	149
Device	73
Biological\|placebo	49
Biological	39
Procedure	34
Dietary Supplement	22
Dietary Supplement\|placebo	20
Device\|Drug	18
Behavioral\|Other	14
Drug\|Other	12
Device\|Other	10
Diagnostic Test	9
Device\|placebo	7
Drug\|Procedure	7
Other\|placebo	5
Behavioral\|Device	4
Combination Product	4
Dietary Supplement\|Drug	4
Behavioral\|Drug	3
Biological\|Drug	3
Dietary Supplement\|Other	3
Drug\|Other\|placebo	3
Other\|Procedure	3
Behavioral\|placebo	2
Biological\|Drug\|placebo	2
Biological\|Other	2
Biological\|Procedure	2
Diagnostic Test\|Other	2
Drug\|placebo\|Radiation	2
placebo	2
Behavioral\|Device\|Other	1
Behavioral\|Drug\|Other	1
Biological\|Device\|Other\|Procedure	1
Biological\|Dietary Supplement	1
Biological\|Drug\|Radiation	1
Biological\|Other\|placebo	1
Combination Product\|placebo	1
Device\|Drug\|Other	1
Device\|Other\|placebo	1
Device\|Other\|Procedure	1
Device\|Procedure	1
Dietary Supplement\|Other\|placebo	1
Drug\|placebo\|Procedure	1
Drug\|Radiation	1
Genetic	1
Genetic\|Other	1
Radiation	1

Count of Versions	Count of Studies
1	142
2	185
3	225
4	193
5	173
6	135
7	127
8	106
9	76
10	49
11	47
12	32
13	26
14	28
15	22
16	13
17	15
18	9
19	7
20	18
21	10
22	10
23	8
24	11
25	13
26	4
27	8
28	4
29	7
30	7
32	5
33	8
34	7
35	1
36	3
37	2
38	1
39	2
40	4
41	4
42	2
43	2
44	6
45	2
46	1
47	1
48	2
49	3
50	2
51	2
53	2
54	1
55	4
57	1
58	4
61	5
62	2
63	2
64	1
65	1
66	2
71	3
73	1
74	1
77	2
79	2
80	1
82	1
83	1
84	1
85	1
90	1
92	1
94	1
99	1
103	1
104	1
106	2
107	1
112	1
139	1
166	1
503	1

Count of Versions	Count of Studies
1	57
2	105
3	95
4	54
5	42
6	28
7	15
8	23
9	6
10	13
11	10
12	5
13	5
14	2
15	2
16	3
17	3
18	2
19	2
20	2
21	1
22	1
23	1
24	1
27	1
28	2
31	1
37	1
39	1
42	1
80	1
89	1
104	1
138	1
174	1

Count of Versions	Count of Studies
1	142
2	185
3	225
4	193
5	173
6	135
7	127
8	106
9	76
10	49
11	47
12	32
13	26
14	28
15	22
16	13
17	15
18	9
19	7
20	18
21	10
22	10
23	8
24	11
25	13
26	4
27	8
28	4
29	7
30	7
32	5
33	8
34	7
35	1
36	3
37	2
38	1
39	2
40	4
41	4
42	2
43	2
44	6
45	2
46	1
47	1
48	2
49	3
50	2
51	2
53	2
54	1
55	4
57	1
58	4
61	5
62	2
63	2
64	1
65	1
66	2
71	3
73	1
74	1
77	2
79	2
80	1
82	1
83	1
84	1
85	1
90	1
92	1
94	1
99	1
103	1
104	1
106	2
107	1
112	1
139	1
166	1
503	1

Count of Versions	Count of Studies
1	57
2	105
3	95
4	54
5	42
6	28
7	15
8	23
9	6
10	13
11	10
12	5
13	5
14	2
15	2
16	3
17	3
18	2
19	2
20	2
21	1
22	1
23	1
24	1
27	1
28	2
31	1
37	1
39	1
42	1
80	1
89	1
104	1
138	1
174	1

asthma

Study Counts

Studies over Time

Interventional Trials

Intervention Type

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Studies by Country

Sites per Study

Phase

Number of Arms

Number of Updates

Update History Change Type

Enrollment Metrics by Phase

Trial Group Type

Intervention Model

Primary Purpose

Observational Studies

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Observation Model

Time Perspective

Registries

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Registry Model

Time Perspective

Follow-up

Count of Versions	Count of Studies
1	142
2	185
3	225
4	193
5	173
6	135
7	127
8	106
9	76
10	49
11	47
12	32
13	26
14	28
15	22
16	13
17	15
18	9
19	7
20	18
21	10
22	10
23	8
24	11
25	13
26	4
27	8
28	4
29	7
30	7
32	5
33	8
34	7
35	1
36	3
37	2
38	1
39	2
40	4
41	4
42	2
43	2
44	6
45	2
46	1
47	1
48	2
49	3
50	2
51	2
53	2
54	1
55	4
57	1
58	4
61	5
62	2
63	2
64	1
65	1
66	2
71	3
73	1
74	1
77	2
79	2
80	1
82	1
83	1
84	1
85	1
90	1
92	1
94	1
99	1
103	1
104	1
106	2
107	1
112	1
139	1
166	1
503	1

Count of Versions	Count of Studies
1	57
2	105
3	95
4	54
5	42
6	28
7	15
8	23
9	6
10	13
11	10
12	5
13	5
14	2
15	2
16	3
17	3
18	2
19	2
20	2
21	1
22	1
23	1
24	1
27	1
28	2
31	1
37	1
39	1
42	1
80	1
89	1
104	1
138	1
174	1